一、基本情况

柯应根，博士，副教授，硕士生导师

电子邮箱：ygke(at)hubu.edu.cn

研究领域：水稻分子生物学

研究方向：水稻调控“生长-抗逆”间平衡的分子机制；水稻对高温的响应机制及水稻耐高温基因的挖掘

二、教育背景

2005.09–2014.04  华中农业大学，作物遗传改良国家重点实验室，博士

2001.09–2005.07  华中农业大学，生命科学技术学院，学士

三、工作经历

2020.11至今          九游会老哥俱乐部，省部共建生物催化与酶工程国家重点实验室，副研究员

2014.07–2020.06  华中农业大学，作物遗传改良国家重点实验室，博士后/副研究员

四、科研项目

1. 国家自然科学基金，青年基金，解析水稻OsPAD4基因调控茉莉酸合成抗白叶枯菌的分子机制，2016.01-2018.12，20万，已结题，主持

2. 博士后基金，特别第9批，2016T90703，解析水稻茉莉酸和油菜素内酯之间信号网络的调控机制，15万，已结题，主持

3. 博士后基金，面上资助第58批，2015M582239，解析OsKYG1调控水稻抗病和水稻发育的分子机制，5万，已结题，主持

五、代表性论文

1. Ke Y, Yuan M, Liu H, Hui S, Qin X, Chen J, Zhang Q, Li X, Xiao J, Zhang Q*, Wang S* (2020). The versatile functions of OsALDH2B1 provide a genic basis for growth-defense tradeoffs in rice. Proceedings of the National Academy of Sciences of the United States of America 117, 3867-3873.

2. Li B, Sun S, Gao X, Wu M, Deng Y, Zhang Q, Li X, Xiao J, Ke Y*, Wang S* (2019). Overexpression a “fruit-weight 2.2-like” gene OsFWL5 improves rice resistance. Rice 12, 51.

3. Ke Y, Kang Y, Wu M, Liu H, Hui S, Zhang Q, Li X, Xiao J, Wang S* (2019) Jasmonic acid-involved OsEDS1 signaling in rice-bacteria interactions. Rice 12, 25.

4. Ke Y, Wu M, Zhang Q, Li X, Xiao J, Wang S* (2019) Hd3a and OsFD1 negatively regulate rice resistance to Xanthomonas oryzae pv. oryzae and Xanthomonas oryzae pv. oryzicola. Biochemical and Biophysical Research Communications 513, 775-780.

5. Ke Y, Deng H, Wang S* (2017) Advances in understanding broad-spectrum resistance to pathogens in rice. The Plant Journal 90, 738–748.

6. Hu K, Cao J, Zhang J, Xia F, Ke Y, Zhang H, Xie W, Liu H, Cui Y, Cao Y, Sun X, Xiao J, Li X, Zhang Q, Wang S* (2017) Improvement of multiple agronomic traits by a disease resistance gene via cell wall reinforcement. Nature Plants 3, 17009.

7. Ke Y, Hui S, Yuan M* (2017) Xanthomonas oryzae pv. oryzae inoculation and growth rate on rice by leaf clipping method. Bio-protocol DOI:10.21769/BioProtoc.

8. Yuan M, Ke Y, Huang R, Ma L, Yang Z, Chu Z, Xiao J, Li X, Wang S* (2016) A host basal transcription factor is a key component for infection of rice by TALE-carrying bacteria. eLife 5, e19605.

9. Ke Y, Liu H, Li X, Xiao J, Wang S* (2014) Rice OsPAD4 functions differently from Arabidopsis AtPAD4 in hostpathogen interactions. The Plant Journal 78, 619–631.

六、授权专利：

1. 王石平、柯应根。水稻抗病相关基因OsPAD4。专利号：ZL201310753446.7